Defoaming agent P220 ,P952 used for indutry fermentation processing, .It will not have impact to the fermentation microorganism, low dosgae with strong disperses property, and extremely low surface tension . 

　　Industrial fermentation bubbling is caused by many reasons, the main reasons can be divided into the following three points: first, the physical stirring equipment is unreasonable or the stirring time is too long will lead to the production of foam.Second is the metabolic reaction of microorganisms. When there are too many microorganisms growing in the culture medium, their metabolism will be very frequent, easily leading to the production of foam.The end, the change of temperature environment will also lead to the production of foam, affecting the progress of industrial fermentation.

　　Polyether based defoaming agent P220 and Polyether based antifoam agent P952they are specially designed for solving industrial fermentation foams, it can effectively solve the problem of bubble, according to the biological fermentation process characteristics, can be added in the fermentation base material, or after high temperature sterilization , fermetation defoamer added in the base material have better effect than added in the subsequent fermentation, and with longer inhibit time.